“Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.”National Human Genome Research Institute (NHGRI)
A DNA sequencer “reads” a molecule of DNA to generate the sequence of As, Cs, Gs and Ts that it encodes. In a nanopore sequencer, this is performed by passing a DNA molecule through a tiny hole called a nanopore. As the molecule moves through the pore, a sensor can detect which of the bases (A, C, G or T) is passing through.
Our Brickopore sequencer works in the same way – the Lego bricks are passed through a hole and a sensor detects the colour of each brick as it moves through. The series of colours is then converted to a sequence of letters.